{"product_id":"catalax","title":"Cartalax","description":"\u003cp data-start=\"837\" data-end=\"1105\"\u003eCartalax (alanine-glutamic acid-aspartic acid) is a short-chain synthetic peptide derived from cartilage-specific protein fragments and is increasingly utilized in preclinical research of cartilage biology, connective-tissue aging, and extracellular-matrix regulation.\u003c\/p\u003e\n\u003cp data-start=\"1107\" data-end=\"1835\"\u003eIn laboratory research, Cartalax has shown activity in \u003cstrong data-start=\"1162\" data-end=\"1194\"\u003echondrocytes and fibroblasts\u003c\/strong\u003e, where it appears to upregulate synthesis of structural proteins such as type II collagen and aggrecan while simultaneously reducing expression of matrix-degrading enzymes (MMP-9\/MMP-13) in models of cartilage degeneration.  Its small size enables uptake into cells and potential modulation of gene networks tied to tissue repair and senescence: for example, studies suggest Cartalax may influence expression of cell-cycle regulators (p16^INK4a, p21) and sirtuin-related pathways (SIRT1), which are associated with cellular aging in cartilage and connective tissue. \u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-start=\"1837\" data-end=\"2610\"\u003eCartalax has also been explored in models of mechanical and oxidative stress on cartilage tissue: in chondrocyte culture systems subjected to compression or oxidative insult, Cartalax treatment corresponded with higher mitochondrial membrane potential, reduced reactive-oxygen species levels, and decreased apoptosis markers like caspase-3. These findings suggest a protective role under stress conditions. Additionally, the peptide is being evaluated for its role in joint-related aging: by modulating fibroblast activity, extracellular-matrix balance, and pro-inflammatory cytokines (e.g., TNF-α, IL-6), Cartalax may serve as a tool in studying cartilage resilience and age-related degeneration. \u003cspan class=\"\" data-state=\"closed\"\u003e\u003cspan class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-start=\"2612\" data-end=\"3156\"\u003eIn terms of tissue-engineering and biomaterials research, Cartalax’s ability to act as a bioregulator in cartilage explants and scaffold models has attracted interest: researchers have tested its integration into hydrogel systems, observing improved proteoglycan retention and reduced glycosaminoglycan release in treated specimens. These findings support its potential as a peptide probe in regenerative biology, particularly in studies targeting cartilage repair, joint biomechanics, and matrix turnover.\u003c\/p\u003e\n\u003cp data-start=\"3158\" data-end=\"3464\"\u003eWhile Cartalax remains a research tool, the emerging evidence positions it as a useful compound for scholars investigating cartilage integrity, connective-tissue aging, and multi-factorial repair pathways, especially when combined with advanced imaging, gene-expression profiling, and biomechanical assays.\u003c\/p\u003e","brand":"Chroma23® Peptides","offers":[{"title":"20mg","offer_id":47042106949867,"sku":"CAT-AX-C23","price":166.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0791\/1332\/2731\/files\/CRT-Chroma-VIal.jpg?v=1765930267","url":"https:\/\/www.chroma23peptides.com\/products\/catalax","provider":"Chroma23® Peptides","version":"1.0","type":"link"}