{"product_id":"epithalon","title":"Epithalon","description":"\u003cp\u003eEpithalon, also known as Epitalon (Ala-Glu-Asp-Gly), is a pineal-derived synthetic peptide that has been the subject of extensive research in cellular aging, telomere science, and regulatory peptide biology. A seminal in vitro study demonstrated that Epithalon induces significant \u003cstrong\u003etelomerase activity and telomere elongation\u003c\/strong\u003e in human somatic cells. Treated fibroblasts exhibited activation of the telomerase catalytic subunit and extended telomere length beyond the standard Hayflick limit, indicating potential for extended cellular lifespan (\u003ca title=\"[PDF] Epithalamin\/Epithalon - Alzheimer's Drug Discovery Foundation\" href=\"https:\/\/www.alzdiscovery.org\/uploads\/cognitive_vitality_media\/Epithalamin-and-Epithalon-Cognitive-Vitality-For-Researchers.pdf?utm_source=chatgpt.com\"\u003eAlzheimer's Drug Discovery Foundation\u003c\/a\u003e, \u003ca title=\"Epithalon Peptide and Telomere Science: A New Frontier in Anti-Aging\" href=\"https:\/\/revolutionhealth.org\/blogs\/news\/epithalon-peptide-telomerase-anti-aging?utm_source=chatgpt.com\"\u003eRevolution Health \u0026amp; Wellness\u003c\/a\u003e, \u003ca title=\"Melatonin and Pineal Gland Peptides Are Able to Correct the Impai...\" href=\"https:\/\/www.ingentaconnect.com\/content\/ben\/cas\/2012\/00000005\/00000003\/art00003?utm_source=chatgpt.com\"\u003eIngenta Connect\u003c\/a\u003e, \u003ca title=\"Epithalon peptide induces telomerase activity and ... - PubMed\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12937682\/?utm_source=chatgpt.com\"\u003ePubMed\u003c\/a\u003e). Research in animal models and human cohorts has revealed that Epithalon may \u003cstrong\u003esupport pineal gland function and melatonin production\u003c\/strong\u003e, which frequently declines with age. In aged primates and elderly participants, treatment with this peptide was associated with normalized melatonin synthesis and improved circadian rhythm regulation (\u003ca title=\"Experimental Studies of the Pineal Gland Preparation Epithalamin\" href=\"https:\/\/www.researchgate.net\/publication\/289987732_Experimental_Studies_of_the_Pineal_Gland_Preparation_Epithalamin?utm_source=chatgpt.com\"\u003eResearchGate\u003c\/a\u003e, \u003ca title=\"Pineal peptides restore the age-related disturbances in hormonal ...\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15664732\/?utm_source=chatgpt.com\"\u003ePubMed\u003c\/a\u003e). Additional studies have explored its \u003cstrong\u003eantioxidant and immune-supportive effects\u003c\/strong\u003e. In aging oocyte models, Epithalon increased antioxidant enzyme activity (such as superoxide dismutase), reduced reactive oxygen species (ROS), and preserved cellular morphology, suggesting protective effects against oxidative stress in aging cells (\u003ca title=\"Epitalon protects against post-ovulatory aging-related damage of ...\" href=\"https:\/\/www.aging-us.com\/article\/204007\/text?utm_source=chatgpt.com\"\u003eAging-US\u003c\/a\u003e). Epithalon’s compact tetrapeptide structure and chemical stability make it well-suited for laboratory investigations across in vitro and in vivo systems, including research on DNA stability, immune aging, sleep modulation, and cellular senescence pathways.\u003c\/p\u003e","brand":"Chroma23® Peptides","offers":[{"title":"50","offer_id":47008783499499,"sku":"EPT-50-C23","price":456.0,"currency_code":"USD","in_stock":true},{"title":"10","offer_id":47042099904747,"sku":"EPT-10-C23","price":166.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0791\/1332\/2731\/files\/EPT-Chroma-VIal.jpg?v=1765930304","url":"https:\/\/www.chroma23peptides.com\/products\/epithalon","provider":"Chroma23® Peptides","version":"1.0","type":"link"}