{"product_id":"vip","title":"VIP","description":"\u003cp data-start=\"1169\" data-end=\"1598\"\u003eVasoactive Intestinal Peptide (VIP) is a multifunctional neuropeptide belonging to the secretin\/glucagon peptide family. Since its discovery, VIP has been recognized as a key signaling molecule linking the nervous, immune, and endocrine systems. It exerts its biological effects primarily through VPAC1 and VPAC2 receptors, which are widely expressed across immune cells, epithelial tissues, smooth muscle, and neural structures.\u003c\/p\u003e\n\u003cp data-start=\"1600\" data-end=\"2045\"\u003eOne of the most extensively studied properties of VIP is its ability to regulate inflammatory signaling. In multiple experimental models, VIP suppresses the production of pro-inflammatory cytokines such as TNF-α, IL-6, and IL-12 while promoting anti-inflammatory mediators like IL-10. This dual regulatory role makes VIP an important research peptide for investigating immune tolerance, chronic inflammation, and autoimmune signaling mechanisms.\u003c\/p\u003e\n\u003cp data-start=\"2047\" data-end=\"2523\"\u003eVIP also plays a significant role in gastrointestinal research. It influences intestinal motility, epithelial secretion, and mucosal barrier integrity. Studies have shown that VIP contributes to maintaining gut homeostasis by modulating immune cell activity within the intestinal environment and supporting epithelial cell survival. These properties have positioned VIP as a subject of interest in research related to inflammatory bowel conditions and gut–immune interactions.\u003c\/p\u003e\n\u003cp data-start=\"2525\" data-end=\"2842\"\u003eIn the respiratory system, VIP has been studied for its effects on smooth muscle relaxation and inflammatory control. Experimental data suggest VIP can reduce airway inflammation, inhibit immune cell infiltration, and support epithelial repair, making it relevant in pulmonary and airway inflammation research models.\u003c\/p\u003e\n\u003cp data-start=\"2844\" data-end=\"3213\"\u003eNeurological research highlights VIP’s neuroprotective and neuromodulatory roles. VIP influences neuronal survival, synaptic plasticity, and circadian rhythm regulation through its action in the hypothalamus and cortex. It has also been studied in models of neuroinflammation and neurodegeneration, where it appears to reduce microglial activation and oxidative stress.\u003c\/p\u003e\n\u003cp data-start=\"3215\" data-end=\"3507\"\u003eAt the cellular level, VIP has been shown to support mitochondrial function, reduce oxidative damage, and regulate apoptosis-related pathways. These effects extend its relevance into metabolic research, aging-related cellular studies, and investigations focused on cellular stress resilience.\u003c\/p\u003e\n\u003cp data-start=\"3509\" data-end=\"3672\"\u003eCollectively, VIP is valued in research for its broad signaling capabilities and its role as a central coordinator of immune, neural, and epithelial communication.\u003c\/p\u003e","brand":"Chroma23® Peptides","offers":[{"title":"10mg","offer_id":47189847179499,"sku":"VIP-96-C23","price":366.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0791\/1332\/2731\/files\/VIP-Chroma-VIal.jpg?v=1765930228","url":"https:\/\/www.chroma23peptides.com\/products\/vip","provider":"Chroma23® Peptides","version":"1.0","type":"link"}